Deep Array Probes

Next-generation miniature electrode arrays designed from the ground-up to reach deep targets in non-human primates without compromising on ease of use or high-channel-count

Non-human primate (NHP) and large animal electrophysiology has been hindered by a relative lack of tools that can record plentiful neurons much deeper than the cortex and withstand the rigours of use in NHP models... Our new Deep Array Probes overcome these hurdles with up to 128 electrodes tailored for high-resolution single unit recording (and multi-laminar read-out) on a minimally-invasive stainless steel backbone with a customisable reach up to 90 mm. Furthermore, you can also enable your Deep Array with a range of fiber optic cannula choices for combined electrophysiology and optogenetics too.

Deep Array probes can be readily used in traditional head-fixed NHP setups and also can be paired with wireless telemetry for unconstrained, freely-behaving animal setups too, as demonstrated recently by Abbaspoor and Hoffman (2024) in Cell Reports. Equipped with either traditional Omnetics connectors or integrated Intan pre-amplifier chips which digitise signals with efficiency and excellent noise-rejection (which can be configured to utilise the steel backbone of the Deep Arrayn as a local GND electrode) you experiments will benefit from high-yield, high-quality single unit and LFP recording across a range superficial to deep brain targets.

Deep Array probes can able so be supplied with custom guide tubes to enable efficient and seamless penetration through the dura, and they may also be used with your own preferred guide tube systems. Furthermore, there's no need to stop a single Deep Array per animal either as you can readily add multiple probes to address multiple targets, subject to the usual mechanical considerations surrounding your chosen head-plate / chamber system.

Whether you are probing the depths of the brainstem or teasing apart cortical computations, the Deep Array is the ultimate tool for exploring the NHP brain

Many aspects of the Deep Array's physical configuration can be adapted to fit your workflow, including length, grounding configuration, attachment points for mounting on your manipulators or our nano-Drives, and so on. You can easily transform your Deep Array probe into an advanced optrode choosing from a wide range of fiber cannula choices, enabling you to deliver light directly to the neurons being recorded. What sets our optrodes apart is their engineered resistance to photoelectric stimulation artifacts, ensuring optimal performance.